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Rabbit Anti-Neurotensin antibody
Rabbit Anti-Neurotensin antibody
Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN; Large neuromedin N; Neuromedin N preproprotein; NMN 125; NMN-125; NN; Tail peptide; NN; Neurotensin/neuromedin N.
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  • NO.:SL0072R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,)
    Applications:ELISA IHC-P IHC-F IF
    concentration:1mg/ml
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Product Name Neurotensin
Chinese Name 神经降压素抗体
Alias Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN;   Large neuromedin N; Neuromedin N preproprotein; NMN 125; NMN-125; NN; Tail peptide; NN; Neurotensin/neuromedin N.
Research Area Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 1.7/19kDa
Cellular localization cytoplasmic Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide (QLYENKPRRPYIL-C) 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.

Function:
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.

Similarity:
Belongs to the neurotensin family.

SWISS:
P30990

Gene ID:
4922

Database links:

Entrez Gene: 280881 Cow

Entrez Gene: 611687 Dog

Entrez Gene: 4922 Human

Entrez Gene: 67405 Mouse

Entrez Gene: 299757 Rat

Omim: 162650 Human

SwissProt: P01156 Cow

SwissProt: P10673 Dog

SwissProt: P30990 Human

SwissProt: Q9D3P9 Mouse

SwissProt: P20068 Rat

Unigene: 80962 Human

Unigene: 64201 Mouse

Unigene: 60814 Rat



神经降压素 Neurotensin, NT 是一种具有生物活性的单链多肽,后来发现NT也存在于人及其它哺乳动物的胃肠道和其它组织中,如肾上腺髓质、甲状腺等。作为一种脑肠肽,具有神经递质、神经调质和局部激素作用。

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