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Product Name Neurotensin Chinese Name 神经降压素抗体 Alias Human proneurotensin; NT; NT/N; NTRH; NTS1; Proneuromedin N mRNA; NEUT_HUMAN; Large neuromedin N; Neuromedin N preproprotein; NMN 125; NMN-125; NN; Tail peptide; NN; Neurotensin/neuromedin N. Research Area Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 1.7/19kDa Cellular localization cytoplasmic Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide (QLYENKPRRPYIL-C) Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
Function:
Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
Subcellular Location:
Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.
Similarity:
Belongs to the neurotensin family.
SWISS:
P30990
Gene ID:
4922
Database links:
Entrez Gene: 4922 Human
Entrez Gene: 67405 Mouse
Omim: 162650 Human
SwissProt: P30990 Human
SwissProt: Q9D3P9 Mouse
Unigene: 80962 Human
Unigene: 64201 Mouse
Unigene: 60814 Rat
神经降压素 Neurotensin, NT 是一种具有生物活性的单链多肽,后来发现NT也存在于人及其它哺乳动物的胃肠道和其它组织中,如肾上腺髓质、甲状腺等。作为一种脑肠肽,具有神经递质、神经调质和局部激素作用。
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