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Product Name Galanin Chinese Name 甘丙肽/神经节肽抗体 Alias GAL 1; GAL; GAL1; Galanin precursor; GALN; GLNN; GMAP; MGC40167; GALA_HUMAN. Research Area Cardiovascular immunology Neurobiology Diabetes Endocrinopathy Immunogen Species Mouse Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 3/13kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Galanin: 33-62/123 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).[supplied by OMIM, Jan 2009]
Function:
Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion.
Subcellular Location:
Secreted.
Similarity:
Belongs to the galanin family.
SWISS:
P22466
Gene ID:
51083
Database links:
Entrez Gene: 51083 Human
Entrez Gene: 14419 Mouse
Omim: 137035 Human
SwissProt: P22466 Human
SwissProt: P47212 Mouse
Unigene: 278959 Human
Unigene: 4655 Mouse
Unigene: 8929 Rat
神经节肽(Galanin)是由30个氨基酸残基组成的神经肽。最初认为只在相当小的背根神经节细胞群体及脊髓神经元中出现,后发现在消化道及胰腺中也广泛分布。与感觉的调整有关,对痛觉传递及脊髓兴奋起抑制作用,在很多禽类动物中有表达,是中枢神经系统及内分泌胰腺的神经调节肽。Product Picture Tissue/cell: rat spinal cord; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-Galanin Polyclonal Antibody, Unconjugated(SL0017M) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0024) and DAB(C-0010) staining
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