Product Name	human CD34/Cy7
Chinese Name	Cy7标记小鼠抗人CD34单克隆抗体
Alias	CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN.
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	4H11
React Species	(predicted: Human, )
Applications	Flow Cyt=5ul/Test, Flow-Cyt=5ul/Test  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	39kDa
Detection molecular weight	105-120
Form	Liquid
immunogen	Recombinant human CD34 protein
Lsotype	Mouse IgG1
Purification	Affinity purified by Protein G
Buffer Solution	0.01M PBS, 0.5%BSA, 0.03% Proclin300
Storage	Store at 2-8℃. Protect from light. Avoid freezing.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The highly glycosylated 75-120 kD antigen CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C, suggesting a putative role in signal transduction. Two isoforms of CD34 have been reported to be generated by alternative splicing. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells, brain, and testis. Staining for CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. SWISS: P28906 Gene ID: 947

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