Product Name	Mouse Anti-Human IgM ascites
Chinese Name	小鼠抗人IgM腹水
Alias	human Immunoglobulin M.  小鼠抗人-IgM;
Immunogen Species	Mouse
Clonality	Polyclonal
React Species	Human,
Applications	WB=1:10000-50000 ELISA=1:10000-100000 IHC-P=1:10000-50000 IHC-F=1:10000-50000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Lyophilized powder
immunogen	Native Human IgM
Lsotype	IgG
Purification	Unpurified
Storage	Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

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