Product Name	Goat Anti-Mouse IgM
Chinese Name	羊抗小鼠IgM
Alias	Mouse Immunoglobulin M; Mo IgM;
literatures	Specific References  (8)     |     SL0368G has been referenced in 8 publications. [IF=5.572] Jiayuan Luo. et al. Effects of saponins isolated from Polygonatum sibiricum on H2O2-induced oxidative damage in RIN-m5F cells and its protective effect on pancreas. FOOD CHEM TOXICOL. 2023 May;175:113724  WB ;  Rat.   PubMed:36935075 [IF=5.44] Zhang, Xiaoru, et al. "Ultrasensitive Photoelectrochemical Immunoassay of Antibody against Tumor-associated Carbohydrate antigen Amplified by Functionalized Graphene Derivates and Enzymatic Biocatalytic Precipitation." Biosensors and Bioelectronics (2014).  other ;  Mouse.   PubMed:24690557 [IF=4.501] Wang Qianhui. et al. Autophagy Induced by Muscarinic Acetylcholine Receptor 1 Mediates Migration and Invasion Targeting Atg5 via AMPK/mTOR Pathway in Prostate Cancer. J ONCOL. 2022;2022:6523195  WB ;  Human.   PubMed:35720225 [IF=4.057] Ranran Liet al. Downregulation of the CB1-Mediated Endocannabinoid Signaling Underlies D-Galactose-Induced Memory Impairment. Front Mol Neurosci . 2020 Jul 28;13:130.  WB ;   PubMed:32848596 [IF=3.73] Zhao, Zhiyi, et al. "Maxadilan prevents apoptosis in iPS cells and shows no effects on the pluripotent state or karyotype." PloS one 7.3 (2012): e33953.  Mouse.   PubMed:22457805 [IF=3.337] Xuesong Wanget al. LncRNA NEAT1 Regulates 5-Fu Sensitivity, Apoptosis and Invasion in Colorectal Cancer Through the MiR-150-5p/CPSF4 Axis. Onco Targets Ther . 2020 Jul 1;13:6373-6383.  WB ;  Human.   PubMed:32669857 [IF=2.028] Wang et al. Characteristics of repaglinide and its mechanism of action on insulin secretion in patients with newly diagnosed type-2 diabetes mellitus. (2018) Medicine.(Baltimore). 97:e12476  IF ;  Mouse.   PubMed:30235745 [IF=1.42] Aboelenain et al. Status of autophagy, lysosome activity and apoptosis during corpus luteum regression in cattle. (2015) J.Reprod.De. 61:229-36  IHC ;  Mouse.   PubMed:25819401
Immunogen Species	Goat
Clonality	Polyclonal
React Species	Mouse,
Applications	WB=1:1000-5000 ELISA=1:2000-10000 IHC-P=1:200-1000 IHC-F=1:200-1000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Lyophilized powder
immunogen	Native Mouse IgM
Lsotype	IgG
Purification	Affinity purified by Protein G
Storage	Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	Immunoglobulin M (IgM) normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.

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