Product Name	Goat Anti-Human IgG H&L
Chinese Name	羊抗人IgG H&L
Alias	Human Immunoglobulin G; hu IgG;
literatures	Specific References  (27)     |     SL0297G has been referenced in 27 publications. [IF=12.545] Peidong Hua. et al. Distributed optical fiber biosensor based on optical frequency domain reflectometry. BIOSENS BIOELECTRON. 2023 May;228:115184   PubMed:36878065 [IF=9.518] He Q et al. Spectral-optical-tweezer-assisted fluorescence multiplexing system for QDs-encoded bead-array bioassay. Biosens Bioelectron. 2019 Mar 15;129:107-117.  Other ;  Human.   PubMed:30685705 [IF=8.11] Shaoquan Zheng. et al. Landscape of cancer-associated fibroblasts identifies the secreted biglycan as a protumor and immunosuppressive factor in triple-negative breast cancer. Oncoimmunology. 2022;11(1):2020984  WB ;  Human.   PubMed:35003899 [IF=7.129] Qianfeng Liu. et al. Perfluoroalkyl substances promote breast cancer progression via ERα and GPER mediated PI3K/Akt and MAPK/Erk signaling pathways. ECOTOX ENVIRON SAFE. 2023 Jun;258:114980  WB ;  Human.   PubMed:37148752 [IF=6.914] Chang N et al. Low cost 3D microfluidic chips for multiplex protein detection based on photonic crystal beads. Lab Chip. 2018 Dec 7;18(23):3638-3644.  3D microfluidic chips ;  Human.   PubMed:30357200 [IF=6.41] Zhang, Si, et al. "A double signal electrochemical Human immunoglobulin G immunosensor based on gold nanoparticles-polydopamine functionalized reduced graphene oxide as a sensor platform and AgNPs/Carbon nanocomposite as signal probe and catalytic substrate." Biosensors and Bioelectronics (2015).  other ;  Human.   PubMed:26556185 [IF=6.208] Zhangcheng Fei. et al. Antibody Assay and Anti-Inflammatory Function Evaluation of Therapeutic Potential of Different Intravenous Immunoglobulins for Alzheimer’s Disease. INT J MOL SCI. 2023 Jan;24(6):5549  ELISA ;   PubMed:36982622 [IF=5.942] Qiao Li. et al. CENPH overexpression promotes the progression, cisplatin resistance, and poor prognosis of lung adenocarcinoma via the AKT and ERK/P38 pathways. AM J CANCER RES. 2023; 13(5): 1682–1697  WB ;  Human.   PubMed:37293159 [IF=5.722] Zou, Xiaopan. et al. ZMIZ2 promotes the development of triple-receptor negative breast cancer. Cancer Cell Int. 2022 Dec;22(1):1-16  WB,IHC ;  Human.   PubMed:35101047 [IF=5.44] Tan, Yuyu, et al. "Proximity-dependent Protein Detection Based on Enzyme-Assisted Fluorescence Signal Amplification." Biosensors and Bioelectronics (2013).  Human.   PubMed:23973935 [IF=5.44] Wu, Lei, et al. "A SERS-based immunoassay with highly increased sensitivity using gold/silver core-shell nanorods." Biosensors and Bioelectronics (2012).  Human.   PubMed:22647534 [IF=5.168] Zhongxiang Tang. et al. Abnormal Gene Expression Regulation Mechanism of Myeloid Cell Nuclear Differentiation Antigen in Lung Adenocarcinoma. BIOLOGY-BASEL. 2022 Jul;11(7):1047  WB ;  Human.   PubMed:10.3390/biology11071047 [IF=5.01] Dong, Peipei, et al. "Ultrathin Gold-Shell Coated Silver Nanoparticles onto a Glass Platform for Improvement of Plasmonic Sensors." ACS Applied Materials & Interfaces (2013).  Other ;  Human.   PubMed:23477284 [IF=4.7] Wang, Chongwen, et al. "Polyethylenimine-interlayered silver-shell magnetic-core microspheres as a multifunctional SERS substrate." Journal of Materials Chemistry C (2015).  other ;  Human.   PubMed:26502285 [IF=4.52] Gao, Zhan, et al. "An amphioxus gC1q protein binds human IgG and initiates the classical pathway: Implications for a C1q‐mediated complement system in the basal chordate." European Journal of Immunology (2014).  WB ;  Human.   PubMed:25174509 [IF=4.472] Xinglei Huang. et al. Downregulation of LncRNA GCLC-1 Promotes Microcystin-LR-Induced Malignant Transformation of Human Liver Cells by Regulating GCLC Expression. TOXICS. 2023 Feb;11(2):162  WB ;  Human.   PubMed:36851037 [IF=4.439] Zhou W et al. Controlled Hierarchical Architecture in Poly [oligo (ethylene glycol) methacrylate-b-glycidyl methacrylate] Brushes for Enhanced Label-free Biosensing.Applied Surface Science. 450;(2018) 236–243.  other ;  Human.   PubMed:doi:10.1016/j.apsusc.2018.04.183 [IF=3.73] Wang, Leilei, et al. "A C1q Domain Containing Protein from Scallop Chlamys farreri Serving as Pattern Recognition Receptor with Heat-Aggregated IgG Binding Activity." PloS one 7.8 (2012): e43289.  Human.   PubMed:22905248 [IF=3.73] Wang, Leilei, et al. "A C1q Domain Containing Protein from Scallop Chlamys farreri Serving as Pattern Recognition Receptor with Heat-Aggregated IgG Binding Activity." PloS one 7.8 (2012): e43289.  Human.   PubMed:22905248 [IF=3.286] Chen X et al. Hydrogel-based microbeads for Raman-encoded suspension array using the reversed-phase suspension polymerization method and ultraviolet light curing. Anal Bioanal Chem. 2020 May;412(12):2731-2741.  Other ;  human.   PubMed:32157359 [IF=3.223] Lina Diao. et al. Direct protein detection in solutions of high ionic strength using polyethylene glycol-modified AlGaN/GaN high electron mobility transistors. 2022 Feb 11  Other ;  Other.   PubMed:10.1002/elan.202100680 [IF=2.67] Hao, Nan, et al. "An electrochemical immunosensing method based on silver nanoparticles." Journal of Electroanalytical Chemistry 656.1 (2011): 50-54.  Human.   PubMed:10.1016/j.jelechem.2011.01.029 [IF=2.5] Wu, Lei, et al. "A reusable biosensor chip for SERS-fluorescence dual mode immunoassay." Third International Symposium on Laser Interaction with Matter. International Society for Optics and Photonics, 2015.  other ;  Human.   PubMed:10.1117/12.2180410 [IF=2.5] Fan, Kequan, et al. "A SERS-based microfluidic immunoassay using an in-situ synthesized gold substrate." Third International Symposium on Laser Interaction with Matter. International Society for Optics and Photonics, 2015.  other ;  Human.   PubMed:10.1117/12.2182132 [IF=1.79] Zhang, Ruohu, et al. "Immunoassays based on surface-enhanced fluorescence using gap-plasmon-tunable Ag bilayer nanoparticle films." Journal of fluorescence 23.1 (2013): 71-77.  ELISA ;  Human.   PubMed:22890683 [IF=1.79] Zhang, Ruohu, et al. "A Straightforward Immunoassay Applicable to a Wide Range of Antibodies Based on Surface Enhanced Fluorescence." Journal of Fluorescence (2013): 1-9.  Other ;  Human.   PubMed:23463294 [IF=1.785] Yu Jian. et al. Long non‑coding RNA SNHG7 facilitates pancreatic cancer progression by regulating the miR‑146b‑5p/Robo1 axis. Exp Ther Med. 2021 Apr;21(4):1-13  IP ;  Human.   PubMed:33680120
Immunogen Species	Goat
Clonality	Polyclonal
React Species	Human,
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Lyophilized powder
immunogen	Native Human IgG
Lsotype	IgG
Purification	Affinity purified by Protein G
Storage	Store at -20℃ stable for 2 years (lyophilized powder). Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

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