Product Name	Mouse Anti-Human IgM
Chinese Name	小鼠抗人IgM单克隆抗体
Alias	human Immunoglobulin M.   鼠抗人-IgM;
Immunogen Species	Mouse
Clonality	Monoclonal
React Species	Human,
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Form	Liquid
immunogen	Human IgM
Lsotype	IgG2a
Purification	affinity purified by Protein A
Buffer Solution	PBS
Storage	Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Product Detail	IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences.
Product Picture	The binding ability of antigen to antibody was detected by direct ELISA. The enzyme-labeled antibody (Anti-Human IgM Antibody-HRP (Cat. SL41524M) specifically binds to HIgM, and has no cross reaction or weak reaction with HIgG1, HIgG4, HIgA and IgG.

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