Product Name	Anti-Myoglobin/RBITC
Chinese Name	罗丹明（RBITC）标记的肌红蛋白抗体
Alias	MYO; MB; MGC13548; PVALB; MYG_HUMAN.
Research Area	Tumour  Cardiovascular  Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	17kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	Purified Human Myoglobin (Natural Human Myoglobin protein)
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Myoglobin is a small heme containing protein responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis. Function: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Similarity: Belongs to the globin family. Database links: Entrez Gene: 4151 Human Entrez Gene: 17189 Mouse Entrez Gene: 59108 Rat Omim: 160000 Human SwissProt: P02144 Human SwissProt: P04247 Mouse SwissProt: Q9QZ76 Rat Unigene: 517586 Human Unigene: 404074 Mouse Unigene: 40511 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肌红蛋白存在于肌肉中，心肌中含量特别丰富，，有较高的组织特异性，是横纹肌的特异性标记物，但对Tumour的敏感性较差。主要用于横纹肌Tumour的诊断与鉴别诊断。少数恶性中胚叶混合瘤、睾丸畸胎瘤、肾母细胞瘤亦可见阳性表达。

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