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Rabbit Anti-DLX2/RBITC Conjugated antibody
Rabbit Anti-DLX2/RBITC Conjugated antibody
DII A; Distal less homeo box 2; Distal less homeobox 2; Distal-less homeobox 2; DLX 2; Dlx2; DLX2_HUMAN; Dlx5; Homeobox protein DLX 2; Homeobox protein DLX-2; Homeobox protein DLX2; Homeobox protein TES 1; Homeobox protein TES-1; Homeobox protein TES1; Te
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  • NO.:SL20452R-RBITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Mouse,(predicted: Rat,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-DLX2/RBITC
Chinese Name 罗丹明(RBITC)标记的同源转录因子DLX2抗体
Alias DII A; Distal less homeo box 2; Distal less homeobox 2; Distal-less homeobox 2; DLX 2; Dlx2; DLX2_HUMAN; Dlx5; Homeobox protein DLX 2; Homeobox protein DLX-2; Homeobox protein DLX2; Homeobox protein TES 1; Homeobox protein TES-1; Homeobox protein TES1; Tes 1; Tes-1; Tes1; zgc.  
Research Area Cell biology  Neurobiology  Signal transduction  Stem cells  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse,  (predicted: Rat, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 34kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human DLX2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Dlx genes are a highly conserved family of six different (Dlx1–6) homeo box-containing genes that share homology with distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. Dlx genes are expressed in spatially and temporally restricted patterns in craniofacial primordia, basal telencephalon and diencephalon, and in distal regions of extending appendages, including the limb and the genital bud. The differential expression of Dlx influences patterning, morphogenesis and histogenesis in these tissues. The Dlx gene products can activate transcription and are localized primarily to the nucleus, although Dlx-5 can be found in the cytoplasm. Dlx proteins influence different stages of proper tissue development, including patterning of the orofacial skeleton (craniofacial ectomesenchyme) and differentiation of structures within and between teeth.

Function:
Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the distal-less homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 1746 Human

Entrez Gene: 13392 Mouse

Omim: 126255 Human

SwissProt: Q07687 Human

SwissProt: P40764 Mouse

Unigene: 419 Human

Unigene: 3896 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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