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Rabbit Anti-QRSL/RBITC Conjugated antibody
Rabbit Anti-QRSL/RBITC Conjugated antibody
2700038P16Rik; C80053; DKFZp564C1278; FLJ10989; FLJ12189; FLJ13447; GatA; Glutaminyl tRNA synthase (glutamine hydrolyzing) like 1; Glutaminyl tRNA synthase like protein 1; Glutamyl tRNA(Gln) amidotransferase subunit A, mitochondrial; MGC105526; OTTMUSP000
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  • NO.:SL21123R-RBITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Sheep,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-QRSL/RBITC
Chinese Name 罗丹明(RBITC)标记的谷氨酰-tRNA合成酶蛋白1抗体
Alias 2700038P16Rik; C80053; DKFZp564C1278; FLJ10989; FLJ12189; FLJ13447; GatA; Glutaminyl tRNA synthase (glutamine hydrolyzing) like 1; Glutaminyl tRNA synthase like protein 1; Glutamyl tRNA(Gln) amidotransferase subunit A, mitochondrial; MGC105526; OTTMUSP00000026615.  
Research Area transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 57kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human QRSL
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
QRSL belongs to the amidase family. Catalytic activity: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. There are two named isoforms.

Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).

Subunit:
Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the amidase family. GatA subfamily.

Database links:

Entrez Gene: 55278 Human

Entrez Gene: 76563 Mouse

Entrez Gene: 309911 Rat

SwissProt: Q9H0R6 Human

SwissProt: Q9CZN8 Mouse

SwissProt: Q5FWT5 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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