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Product Name Anti-QRSL/RBITC Chinese Name 罗丹明(RBITC)标记的谷氨酰-tRNA合成酶蛋白1抗体 Alias 2700038P16Rik; C80053; DKFZp564C1278; FLJ10989; FLJ12189; FLJ13447; GatA; Glutaminyl tRNA synthase (glutamine hydrolyzing) like 1; Glutaminyl tRNA synthase like protein 1; Glutamyl tRNA(Gln) amidotransferase subunit A, mitochondrial; MGC105526; OTTMUSP00000026615. Research Area transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 57kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human QRSL Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
QRSL belongs to the amidase family. Catalytic activity: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. There are two named isoforms.
Function:
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Subunit:
Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the amidase family. GatA subfamily.
Database links:Entrez Gene: 55278 Human
Entrez Gene: 76563 Mouse
SwissProt: Q9H0R6 Human
SwissProt: Q9CZN8 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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