Product Name	Anti-TBC1D10A/RBITC
Chinese Name	罗丹明（RBITC）标记的TBC结构域TB10A蛋白抗体
Alias	dJ130H16.1; dJ130H16.2; EBP50 PDZ interactor of 64 kD; EBP50-PDX interactor of 64 kDa; EPI 64; EPI64; EPI64 protein; Rab27A-GAP-alpha; TB10A_HUMAN; TBC1 domain family member 10A; TBC1D10; TBC1D10A.
Research Area	Cell biology  Signal transduction  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Rabbit, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	57kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TBC1D10A
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: TBC1D10A (TBC1 Domain Family Member 10A) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and TBC/RABGAPs. GO annotations related to this gene include GTPase activator activity and PDZ domain binding. An important paralog of this gene is TBC1D10B. Function: Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A. Subcellular Location: Cell projection > microvillus. Localizes to the microvilli-rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells. Post-translational modifications: Exists in both phosphorylated and non-phosphorylated state. Similarity: Contains 1 Rab-GAP TBC domain. Database links: Entrez Gene: 83874 Human Entrez Gene: 103724 Mouse Entrez Gene: 360968 Rat Omim: 610020 Human SwissProt: Q9BXI6 Human SwissProt: P58802 Mouse Unigene: 655273 Human Unigene: 28140 Mouse Unigene: 105859 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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