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Product Name Anti-STK23/RBITC Chinese Name 罗丹明(RBITC)标记的丝氨酸/苏氨酸蛋白激酶23抗体 Alias SRSF protein kinase 3; Muscle-specific serine kinase 1; Serine/arginine-rich protein-specific kinase 3; SR-protein-specific kinase 3; Serine/threonine-protein kinase 23; SRPK3_HUMAN . Research Area Cell biology Developmental biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 62kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human STK23 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Function:
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.
Tissue Specificity:
Exclusively expressed in skeletal and heart muscle.
Similarity:
Belongs to the protein kinase superfamily.
CMGC Ser/Thr protein kinase family.
Contains 1 protein kinase domain.
Database links:
Entrez Gene: 26576 Human
Entrez Gene: 56504 Mouse
SwissProt: Q9UPE1 Human
SwissProt: Q9Z0G2 Mouse
Unigene: 104865 Human
Unigene: 111904 Mouse
Unigene: 72618 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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