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Rabbit Anti-STK23/RBITC Conjugated antibody
Rabbit Anti-STK23/RBITC Conjugated antibody
SRSF protein kinase 3; Muscle-specific serine kinase 1; Serine/arginine-rich protein-specific kinase 3;SR-protein-specific kinase 3;Serine/threonine-protein kinase 23;SRPK3_HUMAN .
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Details

Product Name Anti-STK23/RBITC
Chinese Name 罗丹明(RBITC)标记的丝氨酸/苏氨酸蛋白激酶23抗体
Alias SRSF protein kinase 3; Muscle-specific serine kinase 1; Serine/arginine-rich protein-specific kinase 3; SR-protein-specific kinase 3; Serine/threonine-protein kinase 23; SRPK3_HUMAN .  
Research Area Cell biology  Developmental biology  Signal transduction  Kinases and Phosphatases  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 62kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human STK23
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Function:
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.

Tissue Specificity:
Exclusively expressed in skeletal and heart muscle.

Similarity:
Belongs to the protein kinase superfamily.
CMGC Ser/Thr protein kinase family.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 508325 Cow

Entrez Gene: 26576 Human

Entrez Gene: 56504 Mouse

Entrez Gene: 100240720 Pig

Entrez Gene: 293854 Rat

SwissProt: Q9UPE1 Human

SwissProt: Q9Z0G2 Mouse

SwissProt: B8Y466 Pig

Unigene: 104865 Human

Unigene: 111904 Mouse

Unigene: 72618 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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