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Rabbit Anti-Plexin D1/RBITC Conjugated antibody
Rabbit Anti-Plexin D1/RBITC Conjugated antibody
KIAA0620; MGC75353; PLEX D1; PLEXD 1; PLEXD1; Plexin-D1; PlexinD1; PLXD1_HUMAN; PLXN D1; PLXND 1; PLXND1; PLXND1 protein.
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  • NO.:SL12739R-RBITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-Plexin D1/RBITC
Chinese Name 罗丹明(RBITC)标记的神经丛蛋白D1抗体
Alias KIAA0620; MGC75353; PLEX D1; PLEXD 1; PLEXD1; Plexin-D1; PlexinD1; PLXD1_HUMAN; PLXN D1; PLXND 1; PLXND1; PLXND1 protein.  
Research Area Cardiovascular  Cell biology  Neurobiology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 208kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Plexin D1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E.

Subunit:
Interacts with NRP1, SEMA4A, SEMA3A, SEMA3C and SEMA3E.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes.

Similarity:
Belongs to the plexin family.
Contains 3 IPT/TIG domains.
Contains 1 Sema domain.

Database links:

Entrez Gene: 23129 Human

Entrez Gene: 67784 Mouse

Omim: 604282 Human

SwissProt: Q9Y4D7 Human

SwissProt: Q3UH93 Mouse

SwissProt: Q68HV1 Mouse

SwissProt: Q8VCL8 Mouse

SwissProt: Q9CZF2 Mouse

Unigene: 301685 Human

Unigene: 3085 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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