Product Name	Anti-SLC35D1/RBITC
Chinese Name	罗丹明（RBITC）标记的溶质载体家族蛋白35成员D1抗体
Alias	KIAA0260; MGC138236; S35D1_HUMAN; SLC35D1; Solute carrier family 35 (UDP GlcA/UDP GalNAc transporter), member D1; Solute carrier family 35 (UDP glucuronic acid/UDP N acetylgalactosamine dual transporter), member D1; Solute carrier family 35 member D1; UDP galactose transporter related 7; UDP-galactose transporter-related protein 7; UDP-GlcA/UDP-GalNAc transporter; UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; UGTrel7.
Research Area	Cell biology  Developmental biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Guinea Pig, Cat, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	39kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC35D1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009] Function: Transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to into the endoplasmic reticulum lumen. May participate in glucuronidation and/or chondroitin sulfate biosynthesis. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Ubiquitous. DISEASE: Defects in SLC35D1 are a cause of Schneckenbecken dysplasia (SCHBCKD) [MIM:269250]. Schneckenbecken dysplagia is a rare, autosomal recessive, lethal short-limbed skeletal dysplasia with platyspondylia. Similarity: Belongs to the TPT transporter family. SLC35D subfamily. Database links: Entrez Gene: 613734 Cow Entrez Gene: 23169 Human Entrez Gene: 242585 Mouse Entrez Gene: 733680 Pig Entrez Gene: 298280 Rat Omim: 610804 Human SwissProt: Q9NTN3 Human Unigene: 213642 Human Unigene: 281800 Mouse Unigene: 225024 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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