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Rabbit Anti-LONP2/RBITC Conjugated antibody
Rabbit Anti-LONP2/RBITC Conjugated antibody
Lon peptidase 2, peroxisomal; Lon protease 2; Lon protease homolog 2; Lon protease homolog 2 peroxisomal; Lon protease like protein 2; Lon protease-like protein 2; LONP; lonp2; LONP2_HUMAN; LONPL; MGC4840; Peroxisomal Lon protease; Peroxisomal Lon proteas
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Product Name Anti-LONP2/RBITC
Chinese Name 罗丹明(RBITC)标记的Lon蛋白酶2抗体
Alias Lon peptidase 2, peroxisomal; Lon protease 2; Lon protease homolog 2; Lon protease homolog 2 peroxisomal; Lon protease like protein 2; Lon protease-like protein 2; LONP; lonp2; LONP2_HUMAN; LONPL; MGC4840; Peroxisomal Lon protease; Peroxisomal Lon protease homolog 2; Peroxisomal LON protease like.  
Research Area Cell biology  Signal transduction  Ubiquitin  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 22kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LONP2
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.

Subunit:
Interacts with PEX5. Interacts with TYSND1.

Subcellular Location:
Peroxisome matrix.

Similarity:
Belongs to the peptidase S16 family. Contains 1 Lon domain.


Database links:

Entrez Gene: 83752 Human

Entrez Gene: 66887 Mouse

Entrez Gene: 291922 Rat

SwissProt: Q86WA8 Human

SwissProt: Q9DBN5 Mouse

SwissProt: Q3MIB4 Rat

Unigene: 295923 Human

Unigene: 324550 Mouse

Unigene: 103067 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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