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Rabbit Anti-SIX homeobox 4/RBITC Conjugated antibody
Rabbit Anti-SIX homeobox 4/RBITC Conjugated antibody
AREC 3; AREC3; Homeobox protein SIX4; MGC119450; MGC119452; MGC119453; Sine oculis homeobox homolog 4; SIX4; SIX4_HUMAN.
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Product Name Anti-SIX homeobox 4/RBITC
Chinese Name 罗丹明(RBITC)标记的同源盒蛋白SIX4抗体
Alias AREC 3; AREC3; Homeobox protein SIX4; MGC119450; MGC119452; MGC119453; Sine oculis homeobox homolog 4; SIX4; SIX4_HUMAN.  
Research Area Cell biology  Developmental biology  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Cow, Horse, Sheep, Guinea Pig, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 83kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SIX homeobox 4
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010]

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the SIX/Sine oculis homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 51804 Human

Entrez Gene: 20474 Mouse

Entrez Gene: 299138 Rat

Omim: 606342 Human

SwissProt: Q9UIU6 Human

SwissProt: Q61321 Mouse

Unigene: 690393 Human

Unigene: 97849 Human

Unigene: 249575 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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