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Product Name Anti-Somatostatin Receptor 1/RBITC Chinese Name 罗丹明(RBITC)标记的生长抑素受体1抗体 Alias somatostatin receptor 1; Somatostatin R1; Somatostatin receptor isoform 1; Somatostatin receptor type 1; SRIF 2; SRIF2; SSTR 1; SSTR1; Sstr1; SRIF-2; Smstr-1; Smstr1; sst1; SSR1_HUMAN. Research Area Neurobiology Apoptosis Growth factors and hormones The cell membrane受体 G protein-coupled receptor Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, Guinea Pig, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 43kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SSTR1 C-terminus Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012]
Subunit:
Interacts with SKB1.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:Entrez Gene: 6751 Human
Entrez Gene: 20605 Mouse
Omim: 182451 Human
SwissProt: P30872 Human
SwissProt: P30873 Mouse
Unigene: 248160 Human
Unigene: 278336 Mouse
Unigene: 42915 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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