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Rabbit Anti-Somatostatin Receptor 1/RBITC Conjugated antibody
Rabbit Anti-Somatostatin Receptor 1/RBITC Conjugated antibody
somatostatin receptor 1; Somatostatin R1; Somatostatin receptor isoform 1; Somatostatin receptor type 1; SRIF 2; SRIF2; SSTR 1; SSTR1; Sstr1; SRIF-2; Smstr-1; Smstr1; sst1; SSR1_HUMAN.
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Product Name Anti-Somatostatin Receptor 1/RBITC
Chinese Name 罗丹明(RBITC)标记的生长抑素受体1抗体
Alias somatostatin receptor 1; Somatostatin R1; Somatostatin receptor isoform 1; Somatostatin receptor type 1; SRIF 2; SRIF2; SSTR 1; SSTR1; Sstr1; SRIF-2; Smstr-1; Smstr1; sst1; SSR1_HUMAN.  
Research Area Neurobiology  Apoptosis  Growth factors and hormones  The cell membrane受体  G protein-coupled receptor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Guinea Pig, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 43kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SSTR1 C-terminus
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28. [provided by RefSeq, Jul 2012]

Subunit:
Interacts with SKB1.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 6751 Human

Entrez Gene: 20605 Mouse

Entrez Gene: 25033 Rat

Omim: 182451 Human

SwissProt: P30872 Human

SwissProt: P30873 Mouse

SwissProt: P28646 Rat

Unigene: 248160 Human

Unigene: 278336 Mouse

Unigene: 42915 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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