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Rabbit Anti-Rbms3/RBITC Conjugated antibody
Rabbit Anti-Rbms3/RBITC Conjugated antibody
RBMS3_HUMAN; RNA binding motif, single stranded interacting protein; RNA binding motif, single stranded interacting protein; RNA binding motif, single stranded interacting protein 3; RNA binding protein.
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  • NO.:SL1883R-RBITC
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Cow,Horse,)
    Applications:IF
    concentration:1mg/ml
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Details

Product Name Anti-Rbms3/RBITC
Chinese Name 罗丹明(RBITC)标记的抑癌基因Rbms3抗体
Alias RBMS3_HUMAN; RNA binding motif, single stranded interacting protein; RNA binding motif, single stranded interacting protein; RNA binding motif, single stranded interacting protein 3; RNA binding protein.  
Research Area immunology  Chromatin and nuclear signals  Binding protein  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 48kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Rbms3
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Function:
Binds poly(A) and poly(U) oligoribonucleotides.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Similarity:
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 27303 Human

Entrez Gene: 207181 Mouse

Omim: 605786 Human

SwissProt: Q6XE24 Human

SwissProt: Q8BWL5 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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