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Product Name Anti-IL-20RB/RBITC Chinese Name 罗丹明(RBITC)标记的白介素20受体β链抗体 Alias Interleukin-20 receptor subunit beta; IL-20 receptor subunit beta; IL-20R-beta; IL-20RB; IL20RB; IL-20R2; Il20rb; AV228068; Fndc6; Gm186; Il20R2; MGC130209; DIRS1; Fibronectin type III domain containing 6; FNDC6; I20RB_HUMAN; IL-20R-beta; Interleukin 20 receptor beta; Interleukin 20 receptor beta chain precursor; Interleukin 20 receptor II; Interleukin-20 receptor subunit beta; MGC34923. Research Area immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 34kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-20RB Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009]
Function:
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
Subunit:
Heterodimer with IL20RA and heterodimer with IL22RA1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
Similarity:
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.
Database links:Entrez Gene: 53833 Human
Entrez Gene: 213208 Mouse
Omim: 605621 Human
SwissProt: Q6UXL0 Human
Unigene: 61232 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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