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Product Name Anti-TM7SF2/RBITC Chinese Name 罗丹明(RBITC)标记的脱氢胆固醇还原酶14抗体 Alias ANG1; Another new gene 1 protein; DHCR14A; C 14 sterol reductase; C-14 sterol reductase; Delta 14 SR; Delta(14) sterol reductase; Delta(14)-sterol reductase; Delta-14-SR; DHCR14A; ERG24_HUMAN; NET47; Putative sterol reductase SR 1; Putative sterol reductase SR-1; Sterol C14 reductase; Sterol C14-reductase; TM7SF2; Transmembrane 7 superfamily member 2. Research Area Tumour Cardiovascular Cell biology immunology Chromatin and nuclear signals Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 46kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TM7SF2/DHCR14A Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Function:
Involved in the conversion of lanosterol to cholesterol.
Subcellular Location:
Microsome membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Similarity:
Belongs to the ERG4/ERG24 family.
Database links:
UniProtKB/Swiss-Prot: O76062.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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