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Product Name Anti-Serine carboxypeptidase 1/RBITC Chinese Name 罗丹明(RBITC)标记的丝氨酸羧肽酶1抗体 Alias HSCP 1; HSCP1; likely homolog of rat and mouse retinoid-inducible serine carboxypeptidase; Retinoid inducible serine carboxypeptidase; Retinoid-inducible serine carboxypeptidase precursor; SCP 1; SCP1; SCPEP 1; SCPEP1; Serine carboxypeptidase 1; serine carboxypeptidase 1 precursor protein; RISC_HUMAN. Research Area Cardiovascular Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 48kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RISC/Serine carboxypeptidase 1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Vascular smooth muscle activation is a salient feature of several pathological conditions including atherosclerosis, hypertension, vein graft failure, restenosis, and transplant arteriopathy. Several new genes whose proteins could lead to such biological effects have been identified. One such protein is RISC. Tissue expression pattern of Retinoid-inducible serine carboxypeptidase (RISC) in human revealed that it was highly expressed in kidney and heart.
Function:
May be involved in vascular wall and kidney homeostasis (By similarity).
Subcellular Location:
Secreted (Potential).
Similarity:
Belongs to the peptidase S10 family.
Database links:
Entrez Gene: 59342 Human
Entrez Gene: 74617 Mouse
SwissProt: Q9HB40 Human
SwissProt: Q920A5 Mouse
Unigene: 514950 Human
Unigene: 34126 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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