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Product Name Anti-VIP Receptor 1/RBITC Chinese Name 罗丹明(RBITC)标记的血管活性肠肽受体-1抗体 Alias VIP Receptor1; HVR 1; HVR1; PACAP R 2; PACAP type II receptor; PACAP-R-2; PACAP-R2; Pituitary adenylate cyclase activating polypeptide receptor type II; Pituitary adenylate cyclase activating polypeptide type II receptor; Pituitary adenylate cyclase-activating polypeptide type II receptor; RCD1; RDC 1; RDC1; V1RG; VAPC 1; VAPC1; Vasoactive intestinal peptide receptor 1; Vasoactive intestinal polypeptide receptor 1; Vasoactive intestinal polypeptide receptor 1 precursor; VIP R 1; VIP receptor type I; VIP-R-1; VIPR 1; VIPR; VIPR1; VIPR1_HUMAN; VIRG; VPAC 1; VPAC1; VPCAP1R; FLJ41949. Research Area Tumour Cardiovascular immunology Neurobiology Signal transduction transcriptional regulatory factor Channel protein G protein-coupled receptor TumourCell biologyMaker G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 47kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human VIP Receptor 1/VAPC1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.
Tissue specificity:In lung, HT29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and Tsup-1, but not in the T-cell lines PEER, MOLT-4, HSB and YT.
Subcellular Location:
Cytoplasm. Nucleus.
Tissue Specificity:
Down-regulated in various cancer tissues.
Similarity:
Contains 1 GST C-terminal domain.
Database links:Entrez Gene: 7433 Human
Omim: 192321 Human
SwissProt: P32241 Human
Unigene: 348500 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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