Product Name	Anti-phospho-CK II beta (Ser209)/RBITC
Chinese Name	罗丹明（RBITC）标记的磷酸化丝氨酸/苏氨酸蛋白激酶II β(casein kinase IIβ)抗体
Alias	Casein Kinase 2 beta (phospho S209); Casein Kinase 2 beta (p-S209); p-CSK2B(Ser209); phospho-CSK2B(Ser209); Casein kinase 2 beta polypeptide; casein kinase IIβ; Casein kinase II subunit beta; CK II beta; CK2B; CK2N; CSK2B; CSK2B_HUMAN; CSNK 2B; CSNK2B; G5A; MGC138222; MGC138224; Phosvitin; Protein G5a.
Product Type	Phosphorylated anti
Research Area	Tumour  Cell biology  Signal transduction  Stem cells  Cyclin  transcriptional regulatory factor  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	24kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthesised phosphopeptide derived from human CK II beta around the phosphorylation site of Ser209
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq, Jul 2008]. Function: Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. Subunit: Tetramer composed of an alpha subunit, an alpha' subunit and two beta subunits. The beta subunit dimerization is mediated by zinc ions. Interacts with TCTEX1D3. Interacts with CD163. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Interacts with MUSK; mediates phosphorylation of MUSK by CK2. Post-translational modifications: Phosphorylated by alpha subunit. Similarity: Belongs to the casein kinase 2 subunit beta family. Database links: Entrez Gene: 1460 Human Entrez Gene: 13001 Mouse Entrez Gene: 81650 Rat Omim: 115441 Human SwissProt: P67870 Human SwissProt: P67871 Mouse SwissProt: P67874 Rat Unigene: 73527 Human Unigene: 378901 Mouse Unigene: 137692 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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