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Product Name Anti-Serum Amyloid P/PE Chinese Name PE标记的血清淀粉样蛋白P成份抗体 Alias SAMP; 9.5S alpha 1 glycoprotein; 9.5S alpha 1 glycoprotein; 9.5S alpha-1-glycoprotein; Amyloid P component serum; APCS; MGC88159; Pentaxin related; PTX 2; PTX2; SAMP_HUMAN; SAP; Serum amyloid P component; Serum amyloid P-component(1-203); Serum amyloid P. Research Area immunology Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Pig, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 25-28kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Serum amyloid P component Lsotype IgG Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Product Detail background:
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008].
Subunit:
Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
Subcellular Location:
Secreted.
Tissue Specificity:
Found in serum and urine.
DISEASE:
Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
Database links:Entrez Gene: 325 Human
Omim: 104770 Human
SwissProt: P02743 Human
Unigene: 507080 Human
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