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Product Name Anti-FGF17/PE Chinese Name PE标记的成纤维细胞生长因子17抗体 Alias FGF17; FGF-17; FGF 17; Fibroblast growth factor 17; FGF17_HUMAN. Research Area Tumour Cardiovascular immunology Signal transduction Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 22kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FGF17 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.
Function:
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
Subunit:
Interacts with FGFR3 and FGFR4.
Subcellular Location:
Secreted.
Tissue Specificity:
Preferentially expressed in the embryonic brain.
Similarity:
Belongs to the heparin-binding growth factors family.
Database links:Entrez Gene: 8822 Human
Omim: 603725 Human
SwissProt: O60258 Human
Unigene: 248192 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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