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Rabbit Anti-Kazrin/PE Conjugated antibody
Rabbit Anti-Kazrin/PE Conjugated antibody
HRIHFB2003; KAZ; Kazn; Kazrin; KAZRN_HUMAN; KIAA1026.
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Details

Product Name Anti-Kazrin/PE
Chinese Name PE标记的Kazrin蛋白抗体
Alias HRIHFB2003; KAZ; Kazn; Kazrin; KAZRN_HUMAN; KIAA1026.  
Research Area Cell biology  Signal transduction  Cyclin  Cell differentiation  Cytoskeleton  Extracellular matrix  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 86kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Kazrin
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.

Function:
Component of the cornified envelope of keratinocytes.May be involved in the interplay between adherens junctions anddesmosomes. The function in the nucleus is not known.

Subunit:
Isoform 2, isoform 3 and isoform 4 interact with PPLN-terminus.

Subcellular Location:
Cytoplasm

Tissue Specificity:
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).

Similarity:
Belongs to the kazrin family.
Contains 3 SAM (sterile alpha motif) domains

Database links:

Entrez Gene: 23254 Human

Entrez Gene: 71529 Mouse

Entrez Gene: 313672 Rat

SwissProt: Q674X7 Human

SwissProt: Q69ZS8 Mouse

SwissProt: Q5FWS6 Rat

Unigene: 368823 Human

Unigene: 255986 Mouse

Unigene: 3753 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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