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Rabbit Anti-SOX5/PE-Cy7 Conjugated antibody
Rabbit Anti-SOX5/PE-Cy7 Conjugated antibody
L SOX5; MGC35153; Sex determining region Y box 5; SOX 5; SOX-5;SOX 5 protein; Sox5; SOX5 protein; SOX5_HUMAN; SRY (sex determining region Y) box 5; SRY box 5; Transcription factor SOX 5; Transcription factor SOX-5; Transcription factor SOX5
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Details

Product Name Anti-SOX5/PE-Cy7
Chinese Name PE-Cy7标记的转录因子SOX5抗体
Alias L SOX5; MGC35153; Sex determining region Y box 5; SOX 5; SOX-5; SOX 5 protein; Sox5; SOX5 protein; SOX5_HUMAN; SRY (sex determining region Y) box 5; SRY box 5; Transcription factor SOX 5; Transcription factor SOX-5; Transcription factor SOX5  
Research Area Cell biology  Developmental biology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 84kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SOX5
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Function:
Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 6660 Human

Entrez Gene: 20678 Mouse

Entrez Gene: 140587 Rat

Omim: 604975 Human

SwissProt: P35711 Human

SwissProt: P35710 Mouse

Unigene: 657542 Human

Unigene: 1752 Mouse

Unigene: 482428 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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