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Rabbit Anti-GTPBP1/PE-Cy7 Conjugated antibody
Rabbit Anti-GTPBP1/PE-Cy7 Conjugated antibody
G protein 1; GP 1; GTPB1_HUMAN; GP1; GTP binding protein 1.
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Details

Product Name Anti-GTPBP1/PE-Cy7
Chinese Name PE-Cy7标记的G蛋白Binding protein1抗体
Alias G protein 1; GP 1; GTPB1_HUMAN; GP1; GTP binding protein 1.  
Research Area Signal transduction  transcriptional regulatory factor  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 72kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GTPBP1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008]

Function:
The GTPBP1 gene is upregulated by interferon gamma and the protein is a member of the AGP11/GTPBP1 family of GTP binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. This gene is upregulated by interferon gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype.

Subunit:
Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with AANAT mRNA, but does not bind mRNA by itself (By similarity).

Subcellular Location:
Cytoplasm (By similarity).

Similarity:
Belongs to the GTPBP1 GTP-binding protein family.

Database links:

Entrez Gene: 9567 Human

Entrez Gene: 14904 Mouse

Entrez Gene: 300077 Rat

Omim: 602245 Human

SwissProt: O00178 Human

SwissProt: O08582 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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