Product Name	Anti-IFT81/PE-Cy7
Chinese Name	PE-Cy7标记的细胞纤毛内转运同源蛋白81抗体
Alias	Carnitine deficiency associated expressed in ventricle 1 isoform 2; Carnitine deficiency-associated protein expressed in ventricle 1; CDV-1; CDV1; CDV1R; Ift81; IFT81_HUMAN; intraflagellar transport 81 homolog (Chlamydomonas); Intraflagellar transport protein 81 homolog.
Research Area	Cell biology  immunology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	80kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human IFT81
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: IFT81 is a 676 amino acid protein that is present at high levels in testis and is moderately expressed in heart, liver, ovary, pancreas, kidney and skeletal muscle. Existing as three alternatively spliced isoforms, two of which are designated CDV-1 and CDV-1R, IFT81 plays a role in testicular development and spermatogenesis and may also be involved in cardiac hypertrophy caused by carnitine deficiency. The gene encoding IFT81 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders. Function: Isoform CDV-1 may be involved in cardiac hypertrophy caused by carnitine deficiency (By similarity). Isoform CDV-1R appears to play a role in development of the testis and spermatogenesis (By similarity). Tissue Specificity: Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis. Database links: Entrez Gene: 28981 Human SwissProt: Q8WYA0 Human Unigene: 528382 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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