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Product Name Anti-C1orf38/PE-Cy7 Chinese Name PE-Cy7标记的1号染色体开放阅读框38抗体 Alias Basement membrane induced; Chromosome 1 open reading frame 38; ICB 1; ICB1; Induced by contact to basement membrane 1 protein; Protein ICB 1; Protein THEMIS2; THEMIS2; Thymocyte expressed molecule involved in selection protein 2; THMS2_HUMAN. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 72kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human C1orf38 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
May constitute a control point in macrophage inflammatory response, promoting LPS-induced TNF production.
Subunit:
When phosphorylated, interacts with LYN. Interacts with VAV1 and GRB2 (By similarity).
Tissue Specificity:
Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1.
Post-translational modifications:
Phosphorylation at Tyr-632 is induced by LPS (By similarity).
Similarity:
Belongs to the themis family.
Database links:
UniProtKB/Swiss-Prot: Q5TEJ8.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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