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Rabbit Anti-NME6/PE-Cy7 Conjugated antibody
Rabbit Anti-NME6/PE-Cy7 Conjugated antibody
Inhibitor of p53 induced apoptosis alpha; Inhibitor of p53-induced apoptosis-alpha; IPIA ALPHA; IPIA-alpha; NDK 6; NDK6_HUMAN; NDP kinase 6; NM23 H6; nm23-H6; NM23H6; Nme6.
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Details

Product Name Anti-NME6/PE-Cy7
Chinese Name PE-Cy7标记的P53诱导Apoptosis抑制蛋白α抗体
Alias Inhibitor of p53 induced apoptosis alpha; Inhibitor of p53-induced apoptosis-alpha; IPIA ALPHA; IPIA-alpha; NDK 6; NDK6_HUMAN; NDP kinase 6; NM23 H6; nm23-H6; NM23H6; Nme6.  
Research Area Tumour  Cell biology  Signal transduction  Apoptosis  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 21kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NME6/IPIA ALPHA
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Tissue specificity: Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.

Function:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.

Tissue Specificity:
Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.

Similarity:
Belongs to the NDK family.

Database links:

Entrez Gene: 10201 Human

Entrez Gene: 54369 Mouse

Entrez Gene: 58964 Rat

Omim: 608294 Human

SwissProt: O75414 Human

SwissProt: O88425 Mouse

SwissProt: O88426 Rat

Unigene: 465558 Human

Unigene: 12951 Mouse

Unigene: 36170 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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