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Product Name Anti-SLTM/PE-Cy7 Chinese Name PE-Cy7标记的雌激素诱导的转录调制器抗体 Alias DKFZp762G052; FLJ10005; FLJ13213; MET; Modulator of estrogen induced transcription; SAFB like transcription modulator; SLTM_HUMAN. Research Area Cell biology Signal transduction Apoptosis transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 117 kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from humna SLTM Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
When SLTM is overexpressed it acts as a general inhibitor of transcription that eventually leads to apoptosis.
Function:
When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis.
Subcellular Location:
Nucleus. Note=Detected in punctate structures.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Contains 1 RRM (RNA recognition motif) domain.
Contains 1 SAP domain.
Database links:Entrez Gene: 79811 Human
SwissProt: Q9NWH9 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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