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Rabbit Anti-LCE1A/PE-Cy7 Conjugated antibody
Rabbit Anti-LCE1A/PE-Cy7 Conjugated antibody
Late cornified envelope 1A; Late cornified envelope protein 1A; Late envelope protein 1; LCE1A; LCE1A_HUMAN; LEP1.
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  • NO.:SL9708R-PE-Cy7
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-LCE1A/PE-Cy7
Chinese Name PE-Cy7标记的晚期包膜蛋白1抗体
Alias Late cornified envelope 1A; Late cornified envelope protein 1A; Late envelope protein 1; LCE1A; LCE1A_HUMAN; LEP1.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 11kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human LCE1A
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
LCE1A belongs to the late cornified envelope (LCE) genecluster within the epidermal differentiation complex (EDC) onchromosome 1. The LCE cluster contains multiple conserved genesthat encode stratum corneum proteins, and these genes are expressedrelatively late during fetal assembly of the skin cornifiedenvelope (Jackson et al., 2005 [PubMed 15854049]). For furtherinformation on the LCE gene cluster, see GENE FAMILYbelow.[supplied by OMIM, Feb 2009].

Function:
Precursors of the cornified envelope of the stratum corneum.

Tissue Specificity:
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.

Similarity:
Belongs to the LCE family.

Database links:

Entrez Gene: 353131 Human

Omim: 612603 Human

SwissProt: Q5T7P2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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