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Product Name Anti-HDC/PE-Cy5 Chinese Name PE-Cy5标记的L-组氨酸脱羧酶抗体 Alias L-Histidine decarboxylase; EC 4.1.1.22; HDC; L-HDC; Histidine decarboxylase; DCHS_HUMAN. Research Area immunology Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 74kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HDC Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Histidine decarboxylase(HDC) is the enzyme that calalyses the conversion of histidine into histamine. It can be found in the histamine secreting ECL cells of some species, as well as in the mast cells.The biogenic amine histamine is an important modulator of numerous physiological processes, including neurotransmission, gastric acid secretion and smooth muscle tone.
Function:
Catalyzes the biosynthesis of histamine from histidine.
Subunit:
Homodimer.
Similarity:
Belongs to the group II decarboxylase family.
Database links:Entrez Gene: 3067 Human
Entrez Gene: 15186 Mouse
Omim: 142704 Human
SwissProt: P19113 Human
SwissProt: P23738 Mouse
Unigene: 1481 Human
Unigene: 18603 Mouse
Unigene: 48653 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
主要用于多种变态反应及炎性浸润改变有关的研究。
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