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Rabbit Anti-MTCH1/PE-Cy5.5 Conjugated antibody
Rabbit Anti-MTCH1/PE-Cy5.5 Conjugated antibody
Cell proliferation inducing protein 60; CGI-64; CGI64; Mitochondrial carrier homolog 1; Mitocondrial Carrier Homolog 1; MTCH 1; Mtch1; MTCH1_HUMAN; Presenilin Associated Protein; Presenilin-associated protein; PSAP.
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Product Name Anti-MTCH1/PE-Cy5.5
Chinese Name PE-Cy5.5标记的细胞增殖诱导蛋白60(早老素相关蛋白)
Alias Cell proliferation inducing protein 60; CGI-64; CGI64; Mitochondrial carrier homolog 1; Mitocondrial Carrier Homolog 1; MTCH 1; Mtch1; MTCH1_HUMAN; Presenilin Associated Protein; Presenilin-associated protein; PSAP.  
Research Area Cell biology  Neurobiology  Signal transduction  Apoptosis  Mitochondrion  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Human, Rat, Pig, Guinea Pig, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 42kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human MTCH1
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]

Function:
Potential mitochondrial transporter. May play a role in apoptosis.

Subunit:
Interacts with PSEN1.

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Widely expressed with a predominant expression in brain.

Similarity:
Belongs to the mitochondrial carrier family.
Contains 2 Solcar repeats.

Database links:

Entrez Gene: 23787 Human

Omim: 610449 Human

SwissProt: Q9NZJ7 Human

Unigene: 485262 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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