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Product Name Anti-GBP6/PE-Cy5.5 Chinese Name PE-Cy5.5标记的G蛋白Binding protein6体 Alias DKFZp686G0786; FLJ39135; GBP 6; GBP-6; GBP6; GBP6_HUMAN; GTP binding protein 6; GTP-binding protein 6; Guanine nucleotide binding protein 6; Guanine nucleotide-binding protein 6; Guanylate binding protein 6; Guanylate binding protein family member 6; Guanylate-binding protein 6; GTP-binding protein 6. Research Area Tumour Cell biology Neurobiology Signal transduction G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 72kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GBP6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
GBP6 is a 633 amino acid protein that exists as two alternatively spliced isoforms belonging to the GBP family. GBP6 binds GTP, GDP and GMP, and is encoded by a gene that maps to human chromosome 1p22.2. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Function:
Binds GTP, GDP and GMP.
Similarity:
Belongs to the GBP family.
Database links:
UniProtKB/Swiss-Prot: Q6ZN66.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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