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Rabbit Anti-C1orf38/PE-Cy5.5 Conjugated antibody
Rabbit Anti-C1orf38/PE-Cy5.5 Conjugated antibody
Basement membrane induced; Chromosome 1 open reading frame 38; ICB 1; ICB1; Induced by contact to basement membrane 1 protein; Protein ICB 1; Protein THEMIS2; THEMIS2; Thymocyte expressed molecule involved in selection protein 2; THMS2_HUMAN.
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Product Name Anti-C1orf38/PE-Cy5.5
Chinese Name PE-Cy5.5标记的1号染色体开放阅读框38抗体
Alias Basement membrane induced; Chromosome 1 open reading frame 38; ICB 1; ICB1; Induced by contact to basement membrane 1 protein; Protein ICB 1; Protein THEMIS2; THEMIS2; Thymocyte expressed molecule involved in selection protein 2; THMS2_HUMAN.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 72kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human C1orf38
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
May constitute a control point in macrophage inflammatory response, promoting LPS-induced TNF production.

Subunit:
When phosphorylated, interacts with LYN. Interacts with VAV1 and GRB2 (By similarity).

Tissue Specificity:
Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1.

Post-translational modifications:
Phosphorylation at Tyr-632 is induced by LPS (By similarity).

Similarity:
Belongs to the themis family.

Database links:
UniProtKB/Swiss-Prot: Q5TEJ8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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