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Product Name Anti-Chromogranin B/PE-Cy5.5 Chinese Name PE-Cy5.5标记的嗜铬粒素B抗体 Alias Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B. Research Area Tumour Neurobiology Endocrinopathy Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 72kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CGB Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].
Function:
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
Subcellular Location:
Secreted. Note=Neuroendocrine and endocrine secretory granules.
Tissue Specificity:
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.
Post-translational modifications:
Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.
O-glycosylated.
Similarity:
Belongs to the chromogranin/secretogranin protein family.
Database links:Entrez Gene: 1114 Human
Entrez Gene: 12653 Mouse
Omim: 118920 Human
SwissProt: P05060 Human
SwissProt: P16014 Mouse
Unigene: 516874 Human
Unigene: 11090 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
嗜铬粒素B在肾上腺 垂体 胸腺 子宫 卵巢等神经内分泌组织表达该蛋白成分较多。
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