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Rabbit Anti-Chromogranin B/PE-Cy5.5 Conjugated antibody
Rabbit Anti-Chromogranin B/PE-Cy5.5 Conjugated antibody
Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B.
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  • NO.:SL0543R-PE-Cy5.5
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-Chromogranin B/PE-Cy5.5
Chinese Name PE-Cy5.5标记的嗜铬粒素B抗体
Alias Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B.  
Research Area Tumour  Neurobiology  Endocrinopathy  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 72kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CGB
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].

Function:
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

Subcellular Location:
Secreted. Note=Neuroendocrine and endocrine secretory granules.

Tissue Specificity:
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.

Post-translational modifications:
Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.
O-glycosylated.

Similarity:
Belongs to the chromogranin/secretogranin protein family.

Database links:

Entrez Gene: 1114 Human

Entrez Gene: 12653 Mouse

Entrez Gene: 24259 Rat

Omim: 118920 Human

SwissProt: P05060 Human

SwissProt: P16014 Mouse

SwissProt: O35314 Rat

Unigene: 516874 Human

Unigene: 11090 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

嗜铬粒素B在肾上腺 垂体 胸腺 子宫 卵巢等神经内分泌组织表达该蛋白成分较多。

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