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Product Name Anti-TRP2/PE-Cy5.5 Chinese Name PE-Cy5.5标记的酪氨酸酶相关蛋白2抗体 Alias L dopachrome tautomerase; DCT; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase, tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Delta isomerase; L-dopachrome Delta-isomerase; L-dopachrome tautomerase; TRP 2; TRP-2; TRP2; Tyrosinase related protein 2; Tyrosinase-related protein 2; TYRP2; TYRP2_HUMAN. Research Area immunology Neurobiology Kinases and Phosphatases Synthesis and Degradation Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Pig, Rabbit, Sheep, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 61kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TRP2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Involved in regulating eumelanin and phaeomelanin levels.
Subunit:
Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.
Subcellular Location:
Melanosome membrane; Single-pass type I membrane protein. Melanocytes and retinal pigmented epithelium.
Tissue Specificity:
Melanocytes and retinal pigmented epithelium.
Similarity:
Belongs to the tyrosinase family.
Database links:Entrez Gene: 1638 Human
Entrez Gene: 13190 Mouse
Omim: 191275 Human
SwissProt: P40126 Human
SwissProt: P29812 Mouse
Unigene: 301865 Human
Unigene: 19987 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Synthesis and Degradation(Synthesis and Degradation)
酪氨酸酶相关蛋白-2(tyrosinase related protein-2,TRP-2)又称多巴色素互变异构酶,是一种胞质抗原,与白癜风的病理机制有关.
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