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Product Name Anti-IL22/PE-Cy5.5 Chinese Name PE-Cy5.5标记的白介素-22抗体 Alias Interleukin-22; Il22; IL-22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL23; zcyto18. Research Area immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Dog, ) Applications Flow-Cyt=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 17kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IL-22 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].
Function:
Cytokine that contributes to the inflammatory response in vivo.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-10 family.
Database links:Entrez Gene: 50616 Human
Entrez Gene: 50929 Mouse
Omim: 605330 Human
SwissProt: Q9GZX6 Human
SwissProt: Q9JJY9 Mouse
Unigene: 287369 Human
Unigene: 103585 Mouse
Unigene: 195879 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-22是白介素-10家族的成员,主要是由激活的T lymphocyte产生的一类重要的cell factor,除了在Th17细胞中高表达之外,在NK和NKT等细胞中也有表达,在组织损伤修复以及牛皮癣、肝炎、肺炎、肠炎等慢性炎症中发挥重要作用.IL-22是继IL-6和IL-10之后又一个参与炎症反应和代谢调控的cell factor,IL-22有可能成为干预脂肪肝发生发展的新方法。
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