TEL: +86 571 56623320    EMAIL: [email protected]

Rabbit Anti-SLAMF6/LY108/PE-Cy5.5 Conjugated antibody
Rabbit Anti-SLAMF6/LY108/PE-Cy5.5 Conjugated antibody
LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.
Total
(Vip priceV)
Regular members: $476.8
  • Save more [Favourable] 30% discount
  • NO.:SL2682R-PE-Cy5.5
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,(predicted: Rat,)
    Applications:IF
    concentration:1mg/ml
  • Goods click count:44
  • Product Spec:
  • Quantity: - +
  • Limit points for buying:0 Points
  • Manual
  • Add to cart Inquiry Add to favorite
View History [Clear]

Details

Product Name Anti-SLAMF6/LY108/PE-Cy5.5
Chinese Name PE-Cy5.5标记的SLAMF6抗体
Alias LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.  
Research Area immunology  Cell Surface Molecule  Cell type markers  Natural killer cells  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse,  (predicted: Rat, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 37kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from mouse SLAMF6
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.

Function:
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.

Subunit:
Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Probable).

Tissue Specificity:
Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.

Database links:

Entrez Gene: 114836 Human

Entrez Gene: 30925 Mouse

Omim: 606446 Human

SwissProt: Q96DU3 Human

SwissProt: Q9ET39 Mouse

Unigene: 492348 Human

Unigene: 486404 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Bought notes(bought amounts latest0)

No one bought this product
Total 0 records, divided into1 pages First Prev Next Last

User Comment(Total0User Comment Num)

  • No comment
Total 0 records, divided into1 pages First Prev Next Last
Username: Anonymous user
E-mail:
Rank:
Content:
Verification code: captcha

Call us

+86 571 56623320

Address

Room 1-315, Kongle Changqing Building, No. 160 Guangye Road,Gongshu District, Hangzhou City, Zhejiang Province, China

Join Us with

Leave a message
* To protect against spam, please pass the CAPTCHA test below.