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Product Name Anti-BMP3/PE-Cy5.5 Chinese Name PE-Cy5.5标记的骨形态发生蛋白3抗体 Alias BMP3A; Bone morphogenetic protein 3; Osteogenin. Research Area Tumour Cell biology immunology Growth factors and hormones Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 55kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MMP3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
BMPs (bone morphogenetic proteins) belong to the Transforming Growth Factor beta (TGF beta) superfamily of structurally related signaling proteins. Proteins of the TGF beta superfamily are disulfide linked dimmers composed of two 12-15 kDa polypeptide chains. All the proteins in this superfamily are involved in embryonic development and the maintenance of adult tissue. BMPs initiate, promote and regulate bone development, growth, remodeling and repair. In vivo studies have shown that BMP3 can independently induce cartilage formation.
Database links:
Entrez Gene: 651 Human
Entrez Gene: 110075 Mouse
Omim: 112263 Human
SwissProt: P12645 Human
SwissProt: Q8BHE5 Mouse
Unigene: 387411 Human
Unigene: 209571 Mouse
Unigene: 208979 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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