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Product Name Anti-phospho-p23 (Ser113)/PE-Cy5.5 Chinese Name PE-Cy5.5标记的磷酸化端粒酶Binding proteinP23抗体 Alias Telomerase Binding Protein,P23; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Telomerase-binding protein p23; Hsp90 co-chaperone; Progesterone receptor complex p23; PTGES3; P23; TEBP; TEBP_HUMAN. Product Type Phosphorylated anti Research Area Tumour immunology Signal transduction Apoptosis transcriptional regulatory factor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 18kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated Synthesised phosphopeptide derived from human Telomerase Binding Protein,P23 around the phosphorylation site of Ser113 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.
Function:
Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
Subunit:
Binds to telomerase and to the progesterone receptor.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the p23/wos2 family.
Contains 1 CS domain.
Database links:Entrez Gene: 10728 Human
Entrez Gene: 100043508 Mouse
Entrez Gene: 100048119 Mouse
Entrez Gene: 56351 Mouse
Omim: 607061 Human
SwissProt: Q15185 Human
SwissProt: Q9R0Q7 Mouse
Unigene: 50425 Human
Unigene: 305816 Mouse
Unigene: 2344 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Telomerase Binding Protein,P23是一种端粒酶Binding protein。
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