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Product Name Anti-MMP-23/PE-Cy5.5 Chinese Name PE-Cy5.5标记的基质金属蛋白酶23抗体 Alias Cysteine array matrix metalloproteinase; Femalysin; Matrix metallopeptidase 21; Matrix metallopeptidase 23A (pseudogene); Matrix metallopeptidase 23A; Matrix metallopeptidase 23B; Matrix metalloproteinase 22; Matrix metalloproteinase 23; Matrix metalloproteinase 23B; Matrix metalloproteinase in the female reproductive tract; Matrix metalloproteinase-21; Matrix metalloproteinase-22; Matrix metalloproteinase-23; MIFR 1; MIFR; MIFR-1; MIFR1; MMP 21; MMP 22; MMP 23; MMP 23B; MMP-21; MMP-22; MMP-23; MMP21; MMP22; MMP23_HUMAN; MMP23A; MMP23B; soluble form; Research Area Tumour Cell biology immunology Signal transduction Kinases and Phosphatases Cytoskeleton Extracellular matrix Ubiquitin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 36/44kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MMP-23 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Matrix Metalloproteinase 23 is a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region.
Function:
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type II membrane protein (By similarity). Membrane; Single-pass type II membrane protein. Note=A secreted form produced by proteolytic cleavage may also exist (Probable).
Tissue Specificity:
Predominantly expressed in ovary, testis and prostate.
Post-translational modifications:
N-glycosylated.
Proteolytic cleavage might yield an active form (By similarity).
Similarity:
Belongs to the peptidase M10A family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 8510 Human
Entrez Gene: 26561 Mouse
Omim: 603321 Human
SwissProt: O75900 Human
SwissProt: O88676 Mouse
Unigene: 192316 Human
Unigene: 671760 Human
Unigene: 29373 Mouse
Unigene: 22562 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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