TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-Oncostatin M/PE-Cy5.5 Chinese Name PE-Cy5.5标记的癌基因蛋白抑瘤素M抗体 Alias ONCM_HUMAN; Oncostatin M; Oncostatin M precursor; Oncostatin-M; OSM. Research Area Tumour Cardiovascular Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 26kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Oncostatin M (181-225) Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
Function:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
Subcellular Location:
Secreted.
Similarity:
Belongs to the LIF/OSM family.
Database links:Entrez Gene: 5008 Human
Entrez Gene: 18413 Mouse
Omim: 165095 Human
SwissProt: P13725 Human
SwissProt: P53347 Mouse
Unigene: 248156 Human
Unigene: 131422 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Oncostatin M抑瘤素M。OSM和LIF,G-CSF,IL-6 ,CNTF同属于一组cell factor,是一种调节生长的cell factor。能抑制某些Tumour细胞的生长,但不影响正常细胞。由巨噬细胞和活化Tlymphocyte分泌。
Scan Wechat Qrcode
Scan Whatsapp Qrcode