Product Name	Anti-ABCA9/PE-Cy5.5
Chinese Name	PE-Cy5.5标记的三磷酸腺苷结合盒Transporter9抗体
Alias	ATP binding cassette A9; ATP binding cassette sub family A (ABC1) member 9; ATP binding cassette sub family A member 9; DKFZp686F2450; EST640918; MGC75415; ABCA9_HUMAN.
Research Area	Cell biology  immunology  Signal transduction  Cyclin  Cell differentiation
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Horse, )
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	184kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ABCA9
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA9 is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of the ABCA9 gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. ABCA9 May play a role in monocyte differentiation and lipid homeostasis. Function: May play a role in monocyte differentiation and lipidhomeostasis. Subcellular Location: Membrane; Multi-pass membrane protein(Potential). Tissue Specificity: Widely expressed with higher expression inheart. Similarity: Belongs to the ABC transporter superfamily. ABCAfamily. Contains 2 ABC transporter domains. Database links: Entrez Gene: 10350 Human Entrez Gene: 217262 Mouse Entrez Gene: 287788 Rat Omim: 612507 Human SwissProt: Q8IUA7 Human SwissProt: Q8K449 Mouse Unigene: 131686 Human Unigene: 291459 Mouse Unigene: 98251 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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