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Product Name Anti-SLC19A1/PE-Cy3 Chinese Name PE-Cy3标记的溶质载体家族蛋白19成员A1抗体 Alias CHMD; FLOT 1; FLOT1; Folate transporter 1; FOLT; IFC 1; IFC-1; IFC1; Intestinal folate carrier 1; Intestinal folate carrier; OTTHUMP00000115459; OTTHUMP00000115460; Placental folate transporter; Reduced folate carrier; Reduced folate carrier protein; REFC; RFC 1; RFC; RFC1; S19A1_MOUSE; SLC19A1; Solute carrier family 19 member 1. Research Area Tumour Cell biology Signal transduction Transporter The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Rat, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 64kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from mouse SLC19A1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC19A1 include placental choriocarcinoma and thiamine-responsive megaloblastic anemia syndrome. Among its related pathways are Cell Cycle, Mitotic and Metabolism. GO annotations related to this gene include oxidoreductase activity and folic acid transporter activity. An important paralog of this gene is SLC19A2.
Function:
Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.
Subcellular Location:
Membrane.
Tissue Specificity:
Placenta, liver, and to a much smaller extent, in lung.
Post-translational modifications:
Heavily glycosylated.
Similarity:
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
Database links:Entrez Gene: 6573 Human
Entrez Gene: 20509 Mouse
Omim: 600424 Human
SwissProt: P41440 Human
SwissProt: P41438 Mouse
Unigene: 84190 Human
Unigene: 9042 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Ni*** | 1 | 2024-08-21 |
Ka*** | 1 | 2024-03-16 |
Fr*** | 2 | 2024-01-27 |
Le*** | 1 | 2024-01-01 |
Ma*** | 2 | 2023-10-05 |
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