Product Name	Anti-FXC1/PE-Cy3
Chinese Name	PE-Cy3标记的骨折骨痂蛋白1抗体
Alias	Fracture callus 1 homolog (rat); Fracture callus protein 1; FxC1; Mitochondrial import inner membrane translocase subunit Tim9 B; OTTHUMP00000164584; OTTHUMP00000230720; TIM 10B; Tim10b; Tim9b; T10B_HUMAN; TIMM10B.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	12kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human FXC1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004] Function: Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. Subunit: Component of the TIM22 complex, whose core is composed of TIMM22, associated with peripheral protein TIMM10B/FXC1 and the 70 kDa heterohexamer. In most cases, the 70 kDa complex is composed of TIMM9 and TIMM10. Also forms a complex composed of TIMM9, TIMM10/TIM10A and TIMM10B/FXC1. Subcellular Location: Mitochondrion inner membrane. Tissue Specificity: Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle. Similarity: Belongs to the small Tim family. Database links: Entrez Gene: 26515 Human Omim: 607388 Human SwissProt: Q9Y5J6 Human Unigene: 54943 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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