TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-DUSP23/PE-Cy3 Chinese Name PE-Cy3标记的双特异性磷酸酶抗体23抗体 Alias Dual specificity phosphatase 23; Dual specificity protein phosphatase 23; DUS23_HUMAN; Dusp23; DUSP25; EC 3.1.3.16; EC 3.1.3.48; FLJ20442; LDP 3; LDP-3; LDP3; Low molecular mass dual specificity phosphatase 3; MOSP; RP11-190A12.1; VH1 like member Z; VH1 like phosphatase Z; VH1-like phosphatase Z; VHZ. Research Area Cell biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 17kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DUSP23 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
Subcellular Location:
Cytoplasm; cytosol. Nucleus. Mainly cytosolic. Also nuclear.
Tissue Specificity:
Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.
Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.
Database links:Entrez Gene: 54935 Human
Entrez Gene: 68440 Mouse
SwissProt: Q9BVJ7 Human
SwissProt: Q6NT99 Mouse
Unigene: 425801 Human
Unigene: 33024 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode
Scan Whatsapp Qrcode