Product Name	Anti-COX6B2/PE-Cy3
Chinese Name	PE-Cy3标记的细胞色素C氧化酶蛋白6B2抗体
Alias	Cancer/testis antigen 59; COX VIb-2; Cox6b2; COXVIb-2; COXVIb2; CT59; CX6B2_HUMAN; Cytochrome c oxidase subunit 6B2; Cytochrome c oxidase subunit VIb; Cytochrome c oxidase subunit VIb isoform 2; cytochrome c oxidase subunit VIb polypeptide 2 (testis); Cytochrome c oxidase subunit VIb testes specific; Cytochrome c oxidase subunit VIb, testis-specific isoform; FLJ46422; MGC119094; testis-specific isoform.
Research Area	Tumour  Cell biology  Signal transduction  Cell type markers  The new supersedes the old  Zinc finger protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Cow, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	11kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human COX6B2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines. Function: Connects the two COX monomers into the physiological dimeric form. Subcellular Location: Mitochondrion intermembrane space. Tissue Specificity: Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines. Similarity: Belongs to the cytochrome c oxidase subunit 6B family. Database links: Entrez Gene: 125965 Human Entrez Gene: 333182 Mouse Entrez Gene: 654441 Rat SwissProt: Q6YFQ2 Human SwissProt: Q80ZN9 Mouse SwissProt: Q6YFQ1 Rat Unigene: 550544 Human Unigene: 29625 Mouse Unigene: 97699 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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